MelFish I have my doubts about that. You will need not only CUDA, but also cuDNN, cuBLAS and few other libraries from that package. In any case, Tonfotos compatibility was not tested with this library, and no future support for ZLUDA compatibility is planned.
Actually, since you are using Tonfotos for quite a while already, I would assume you already have your archive fully indexed, so you probably should not worry so much about CUDA support, as its main benefit is during initial indexing stage. After it is finished, it is not that needed.